In the US the population that has the lowest prevalence of alcohol use disorder is...

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Differences in prevalence of alcohol use disorder across racial and ethnic groups reflect biology, culture, and social factors. National data consistently show that Asian American and Pacific Islanders have the lowest prevalence of AUD, a pattern attributed to protective factors such as how alcohol is metabolized in many individuals of these backgrounds (including genetic variations that can produce unpleasant effects and discomfort with drinking), along with cultural norms and expectations that discourage heavy drinking. There can also be underreporting or barriers to access that influence observed rates. By contrast, Native American populations tend to have higher AUD prevalence, with Black and Hispanic groups falling in between, and substantial variation exists within each broader group. Overall, the group with the lowest prevalence is Asian American and Pacific Islanders.