Nervousness or anxiety, sleep difficulty, decreased appetite or weight loss, and depressed mood are signs of:

• A. Nicotine withdrawal
• B. Cannabis withdrawal
• C. Opioid withdrawal
• D. Alcohol withdrawal

Answer: (B)

Nervousness or anxiety, sleep difficulties, decreased appetite with weight loss, and depressed mood are a classic cluster of cannabis withdrawal symptoms. When someone stops regularly using cannabis, the brain’s endocannabinoid system—which has adapted to THC over time—readsjusts. This readjustment often shows up as mood changes, anxiety, trouble sleeping, and changes in appetite, typically beginning within a day or two after stopping, peaking in the first week, and lasting for one to two weeks or more. While anxiety and sleep problems can occur with withdrawals from other substances, the combination of nervousness, sleep trouble, and a notable drop in appetite with weight loss is especially characteristic of cannabis withdrawal.