Which drug is an analog of Demerol?

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Multiple Choice

Which drug is an analog of Demerol?

Meperidine (Demerol) is a synthetic opioid in the phenylpiperidine/amide family. An analog is a compound that shares the same core structural features and belongs to the same class of drugs. MPPP is N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, which preserves the piperidine ring and amide linkage characteristic of meperidine, making it a direct chemical and pharmacological analog. The other options do not share that core structure or activity: MPTP is a toxic byproduct that causes neurodegeneration rather than acting as an analgesic; AMF and PEPAP are not closely related to meperidine in structure or opioid pharmacology. Thus, the analog of Demerol is MPPP.

Meperidine (Demerol) is a synthetic opioid in the phenylpiperidine/amide family. An analog is a compound that shares the same core structural features and belongs to the same class of drugs. MPPP is N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, which preserves the piperidine ring and amide linkage characteristic of meperidine, making it a direct chemical and pharmacological analog. The other options do not share that core structure or activity: MPTP is a toxic byproduct that causes neurodegeneration rather than acting as an analgesic; AMF and PEPAP are not closely related to meperidine in structure or opioid pharmacology. Thus, the analog of Demerol is MPPP.

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